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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Inhibitory Effects of Rosemary Extracts, Carnosic Acid and Rosmarinic Acid on the Growth of Various Human Cancer Cell Lines
|
|---|---|
| Published in |
Plant Foods for Human Nutrition, May 2010
|
| DOI | 10.1007/s11130-010-0166-4 |
| Pubmed ID | |
| Authors |
Ozlem Yesil-Celiktas, Canan Sevimli, Erdal Bedir, Fazilet Vardar-Sukan |
| Abstract |
The leaves of Rosmarinus officinalis harvested from three different locations of Turkey were extracted by both methanolic and supercritical CO(2) extraction. Subsequently, six extracts and the active compounds, carnosic acid, and rosmarinic acid were applied to various human cancer cell lines including NCI-H82 (human, small cell lung, carcinoma), DU-145 (human, prostate, carcinoma), Hep-3B (human, black, liver, carcinoma, hepatocellular), K-562 (human chronic myeloid leukemia), MCF-7 (human, breast, adenocarcinoma), PC-3 (human, prostate, adenocarcinoma) and MDA-MB-231 (human, breast, adenocarcinoma) by MTT assay. Supercritical CO(2) extracts had superior antiproliferative effect compared to the soxhlet extracts. Although the extracts exhibited various cytotoxic effects against different cell lines, comparatively low IC(50) values ranging between 12.50 and 47.55 microg/ml were attained against K-562, being the most sensitive cell line. Moreover, carnosic acid caused the lowest cell viability with values ranging from 13 to 30 % at a concentration of 19 muM after 48 h of treatments, resulting in superior antiproliferative effect. Rosemary extract is a potential candidate to be included in the anti-cancer diet with pre-determined doses avoiding toxicity. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Burkina Faso | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 239 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| French Polynesia | 1 | <1% |
| Ireland | 1 | <1% |
| Lithuania | 1 | <1% |
| Mexico | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 234 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 39 | 16% |
| Student > Ph. D. Student | 34 | 14% |
| Researcher | 24 | 10% |
| Student > Bachelor | 20 | 8% |
| Student > Doctoral Student | 18 | 8% |
| Other | 40 | 17% |
| Unknown | 64 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 18% |
| Biochemistry, Genetics and Molecular Biology | 31 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 10% |
| Medicine and Dentistry | 18 | 8% |
| Chemistry | 17 | 7% |
| Other | 33 | 14% |
| Unknown | 74 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 102. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2020.
All research outputs
#343,960
of 22,713,403 outputs
Outputs from Plant Foods for Human Nutrition
#5
of 701 outputs
Outputs of similar age
#906
of 95,098 outputs
Outputs of similar age from Plant Foods for Human Nutrition
#1
of 3 outputs
Altmetric has tracked 22,713,403 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 701 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,098 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them