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Metabolomics and neuroanatomical evaluation of post-mortem changes in the hippocampus

Overview of attention for article published in Brain Structure and Function, March 2017
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  • Good Attention Score compared to outputs of the same age (68th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

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Title
Metabolomics and neuroanatomical evaluation of post-mortem changes in the hippocampus
Published in
Brain Structure and Function, March 2017
DOI 10.1007/s00429-017-1375-5
Pubmed ID
Authors

Carolina Gonzalez-Riano, Silvia Tapia-González, Antonia García, Alberto Muñoz, Javier DeFelipe, Coral Barbas

Abstract

Understanding the human brain is the ultimate goal in neuroscience, but this is extremely challenging in part due to the fact that brain tissue obtained from autopsy is practically the only source of normal brain tissue and also since changes at different levels of biological organization (genetic, molecular, biochemical, anatomical) occur after death due to multiple mechanisms. Here we used metabolomic and anatomical techniques to study the possible relationship between post-mortem time (PT)-induced changes that may occur at both the metabolomics and anatomical levels in the same brains. Our experiments have mainly focused on the hippocampus of the mouse. We found significant metabolomic changes at 2 h PT, whereas the integrity of neurons and glia, at the anatomical/ neurochemical level, was not significantly altered during the first 5 h PT for the majority of histological markers.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Unknown 78 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 20%
Student > Master 10 13%
Researcher 10 13%
Other 4 5%
Student > Doctoral Student 3 4%
Other 15 19%
Unknown 21 27%
Readers by discipline Count As %
Neuroscience 12 15%
Biochemistry, Genetics and Molecular Biology 8 10%
Agricultural and Biological Sciences 8 10%
Chemistry 6 8%
Medicine and Dentistry 4 5%
Other 15 19%
Unknown 26 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2017.
All research outputs
#6,484,369
of 24,217,893 outputs
Outputs from Brain Structure and Function
#461
of 1,725 outputs
Outputs of similar age
#99,113
of 311,916 outputs
Outputs of similar age from Brain Structure and Function
#13
of 47 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,725 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,916 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.