↓ Skip to main content

Effect of modafinil on cognitive functions in alcohol dependent patients: A randomized, placebo-controlled trial

Overview of attention for article published in Journal of Psychopharmacology, September 2013
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users
peer_reviews
1 peer review site

Citations

dimensions_citation
14 Dimensions

Readers on

mendeley
50 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Effect of modafinil on cognitive functions in alcohol dependent patients: A randomized, placebo-controlled trial
Published in
Journal of Psychopharmacology, September 2013
DOI 10.1177/0269881113503505
Pubmed ID
Authors

Leen Joos, Anna E Goudriaan, Lianne Schmaal, Wim van den Brink, Bernard GC Sabbe, Geert Dom

Abstract

Cognitive deficits are highly prevalent in alcohol-dependent (AD) patients and may have a detrimental impact on treatment response and treatment outcome. Enhancing cognitive functions may improve treatment success. Modafinil is a promising compound in this respect. Therefore, a randomized double-blind placebo-controlled trial was conducted with modafinil (300 mg/d) or placebo in 83 AD patients for 10 weeks. Various cognitive functions (digit span task, Tower of London task, Stroop task) were measured at baseline, during and after treatment. Compared to placebo, modafinil improved verbal short-term memory (number of forward digit spans) (p=0.030), but modafinil exerted a negative effect on the working memory score of the digit span task (p=0.003). However, subgroup analyses revealed that modafinil did improve both working memory and verbal short-term memory in AD patients with a poor working memory ability at baseline (25% worst performers), whereas no significant treatment effect of modafinil was found on these two dependent variables in patients with good working memory skills at baseline (25% best performers). No effect of modafinil was found on measures of planning (Tower of London task) and selective attention (Stroop task). Further research is needed to better understand the relationship between cognitive remediation and treatment outcome in order to design targeted treatments.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Unknown 49 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 18%
Student > Bachelor 6 12%
Professor > Associate Professor 6 12%
Student > Master 6 12%
Student > Doctoral Student 4 8%
Other 8 16%
Unknown 11 22%
Readers by discipline Count As %
Medicine and Dentistry 15 30%
Psychology 10 20%
Agricultural and Biological Sciences 4 8%
Neuroscience 4 8%
Social Sciences 2 4%
Other 1 2%
Unknown 14 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2016.
All research outputs
#2,532,460
of 22,723,682 outputs
Outputs from Journal of Psychopharmacology
#409
of 1,930 outputs
Outputs of similar age
#23,737
of 201,942 outputs
Outputs of similar age from Journal of Psychopharmacology
#3
of 24 outputs
Altmetric has tracked 22,723,682 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,930 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.8. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 201,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.