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Prevalence and molecular characterization of Enterobacteriaceae producing NDM-1 carbapenemase at a military hospital in Pakistan and evaluation of two chromogenic media

Overview of attention for article published in Diagnostic Microbiology & Infectious Disease, December 2012
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Title
Prevalence and molecular characterization of Enterobacteriaceae producing NDM-1 carbapenemase at a military hospital in Pakistan and evaluation of two chromogenic media
Published in
Diagnostic Microbiology & Infectious Disease, December 2012
DOI 10.1016/j.diagmicrobio.2012.11.006
Pubmed ID
Authors

Kathryn M. Day, Shamshad Ali, Irfan Ali Mirza, Hanna E. Sidjabat, Anna Silvey, Clare V. Lanyon, Stephen P. Cummings, Shahid Ahmed Abbasi, Muhammad W. Raza, David L. Paterson, John D. Perry

Abstract

The aim of this study was to assess the frequency and genotypic diversity of carbapenemase-producing Enterobacteriaceae (CPE) in stool samples from patients attending a military hospital in Pakistan. Further aims included the identification of factors that might predispose to faecal carriage and evaluation of 2 chromogenic culture media: Brilliance CRE and chromID CARBA. Of 175 patients, 32 (18.3%) had faecal carriage of CPE and all produced NDM-1 carbapenemase. All of these 32 patients were detected using chromID CARBA compared with 20 patients (62.5%) detected using Brilliance CRE (P = 0.0015). Duration of hospitalization and treatment with co-amoxyclav were statistically associated with a higher likelihood of carriage of CPE (P ≤ 0.05). The majority of NDM-1-producing Enterobacteriaceae co-produced CTX-M-1 group extended spectrum β-lactamase, and one third produced armA-type methylase. NDM-1 carbapenemase was most commonly found amongst commensal types of Escherichia coli, especially phylogenetic group B1.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nigeria 1 1%
Unknown 74 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 20%
Student > Ph. D. Student 13 17%
Student > Bachelor 7 9%
Student > Postgraduate 7 9%
Student > Master 7 9%
Other 12 16%
Unknown 14 19%
Readers by discipline Count As %
Medicine and Dentistry 15 20%
Immunology and Microbiology 13 17%
Agricultural and Biological Sciences 9 12%
Biochemistry, Genetics and Molecular Biology 6 8%
Chemistry 3 4%
Other 5 7%
Unknown 24 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2013.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Diagnostic Microbiology & Infectious Disease
#1,743
of 2,303 outputs
Outputs of similar age
#226,718
of 286,420 outputs
Outputs of similar age from Diagnostic Microbiology & Infectious Disease
#17
of 18 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,303 research outputs from this source. They receive a mean Attention Score of 3.9. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.