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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect
|
|---|---|
| Published in |
Diabetologia, March 2017
|
| DOI | 10.1007/s00125-017-4265-8 |
| Pubmed ID | |
| Authors |
Signe Foghsgaard, Louise Vedtofte, Camilla Andreasen, Emilie S. Andersen, Emilie Bahne, Jonatan I. Bagger, Jens A. Svare, Jens J. Holst, Tine D. Clausen, Elisabeth R. Mathiesen, Peter Damm, Filip K. Knop, Tina Vilsbøll |
| Abstract |
We investigated whether a reduced incretin effect, as observed in patients with type 2 diabetes, can be detected in high-risk individuals, such as women with prior gestational diabetes mellitus (pGDM). In this cross-sectional study, 102 women without diabetes with pGDM and 15 control participants without pGDM and with normal glucose tolerance (NGT) underwent a 4 h 75 g OGTT and an isoglycaemic i.v. glucose infusion (IIGI). Women with pGDM were classified as having NGT or prediabetes (impaired fasting glucose and/or impaired glucose tolerance). Insulin sensitivity was assessed using the Matsuda index and HOMA2-IR and the incretin effect was calculated from insulin responses during the study (100% × [AUCinsulin,OGTT - AUCinsulin,IIGI]/AUCinsulin,OGTT). Sixty-three of the 102 women with pGDM (62%) had prediabetes (median [interquartile range]: age, 38.3 [6.5] years; BMI, 32.1 [5.8] kg/m(2)) and 39 women (38%) had NGT (age, 39.5 [5.6] years; BMI, 31.0 [6.7] kg/m(2)). Control participants (n = 15) were not significantly different from the pGDM group with regards to age (39.2 [7.4] years) and BMI (28.8 [9.2] kg/m(2)). Compared with women with NGT and control participants, women with prediabetes had lower insulin sensitivity, as measured by the Matsuda index (3.0 [2.4] vs 5.0 [2.6] vs 1.5 [1.8], respectively; p < 0.001). The incretin effect was 55.3% [27.8], 73.8% [19.0] and 76.7% [24.6] in women with prediabetes, women with normal glucose tolerance and control participants, respectively (p < 0.01). Prediabetes was highly prevalent in women with pGDM, and alterations in the incretin effect were detected in this group before the development of type 2 diabetes. clinicaltrialsregister.eu 2012-001371-37-DK. |
X Demographics
The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 7 | 28% |
| United States | 3 | 12% |
| Spain | 3 | 12% |
| Serbia | 1 | 4% |
| India | 1 | 4% |
| Brazil | 1 | 4% |
| Germany | 1 | 4% |
| Unknown | 8 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 60% |
| Practitioners (doctors, other healthcare professionals) | 6 | 24% |
| Scientists | 4 | 16% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 74 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 11 | 15% |
| Student > Master | 10 | 14% |
| Student > Ph. D. Student | 9 | 12% |
| Researcher | 5 | 7% |
| Other | 4 | 5% |
| Other | 10 | 14% |
| Unknown | 25 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 31% |
| Nursing and Health Professions | 5 | 7% |
| Biochemistry, Genetics and Molecular Biology | 4 | 5% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Engineering | 3 | 4% |
| Other | 6 | 8% |
| Unknown | 30 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2017.
All research outputs
#2,310,952
of 23,576,969 outputs
Outputs from Diabetologia
#1,207
of 5,134 outputs
Outputs of similar age
#44,988
of 310,301 outputs
Outputs of similar age from Diabetologia
#34
of 67 outputs
Altmetric has tracked 23,576,969 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,134 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,301 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.