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Additive manufacturing of wet-spun polymeric scaffolds for bone tissue engineering

Overview of attention for article published in Biomedical Microdevices, July 2012
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  • Average Attention Score compared to outputs of the same age and source

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1 X user
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1 patent

Citations

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116 Dimensions

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143 Mendeley
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Title
Additive manufacturing of wet-spun polymeric scaffolds for bone tissue engineering
Published in
Biomedical Microdevices, July 2012
DOI 10.1007/s10544-012-9677-0
Pubmed ID
Authors

Dario Puppi, Carlos Mota, Matteo Gazzarri, Dinuccio Dinucci, Antonio Gloria, Mairam Myrzabekova, Luigi Ambrosio, Federica Chiellini

Abstract

An Additive Manufacturing technique for the fabrication of three-dimensional polymeric scaffolds, based on wet-spinning of poly(ε-caprolactone) (PCL) or PCL/hydroxyapatite (HA) solutions, was developed. The processing conditions to fabricate scaffolds with a layer-by-layer approach were optimized by studying their influence on fibres morphology and alignment. Two different scaffold architectures were designed and fabricated by tuning inter-fibre distance and fibres staggering. The developed scaffolds showed good reproducibility of the internal architecture characterized by highly porous, aligned fibres with an average diameter in the range 200-250 μm. Mechanical characterization showed that the architecture and HA loading influenced the scaffold compressive modulus and strength. Cell culture experiments employing MC3T3-E1 preosteoblast cell line showed good cell adhesion, proliferation, alkaline phosphatase activity and bone mineralization on the developed scaffolds.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 <1%
Germany 1 <1%
Italy 1 <1%
Australia 1 <1%
United Kingdom 1 <1%
Unknown 138 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 37 26%
Student > Master 32 22%
Student > Bachelor 16 11%
Researcher 11 8%
Student > Doctoral Student 6 4%
Other 16 11%
Unknown 25 17%
Readers by discipline Count As %
Engineering 44 31%
Materials Science 16 11%
Chemistry 11 8%
Medicine and Dentistry 10 7%
Agricultural and Biological Sciences 8 6%
Other 23 16%
Unknown 31 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2020.
All research outputs
#6,396,976
of 22,727,570 outputs
Outputs from Biomedical Microdevices
#207
of 746 outputs
Outputs of similar age
#44,999
of 164,345 outputs
Outputs of similar age from Biomedical Microdevices
#9
of 17 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 746 research outputs from this source. They receive a mean Attention Score of 4.1. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,345 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.