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Notch signaling is involved in human articular chondrocytes de-differentiation during osteoarthritis

Overview of attention for article published in Journal of Receptor & Signal Transduction Research, November 2013
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Title
Notch signaling is involved in human articular chondrocytes de-differentiation during osteoarthritis
Published in
Journal of Receptor & Signal Transduction Research, November 2013
DOI 10.3109/10799893.2013.856920
Pubmed ID
Authors

Nadia Sassi, Nadia Gadgadi, Lilia Laadhar, Mohamed Allouche, Slim Mourali, Behrouz Zandieh-Doulabi, Moncef Hamdoun, Jenneke Klein Nulend, Sondès Makni, Slaheddine Sellami

Abstract

During osteoarthritis (OA), chondrocytes undergo de-differentiation, resulting in the acquisition of a fibroblast-like morphology, decreased expression of collagen type II (colII) and aggrecan, and increased expression of collagen type I (colI), metalloproteinase 13 (MMP13) and nitric oxide synthase (eNOS). Notch signaling plays a crucial role during embryogenesis. Several studies showed that Notch is expressed in adulthood.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 5%
Unknown 21 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 23%
Researcher 3 14%
Student > Postgraduate 2 9%
Student > Master 2 9%
Professor 1 5%
Other 0 0%
Unknown 9 41%
Readers by discipline Count As %
Medicine and Dentistry 5 23%
Agricultural and Biological Sciences 5 23%
Biochemistry, Genetics and Molecular Biology 4 18%
Unknown 8 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 November 2013.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Journal of Receptor & Signal Transduction Research
#306
of 528 outputs
Outputs of similar age
#277,906
of 315,608 outputs
Outputs of similar age from Journal of Receptor & Signal Transduction Research
#9
of 24 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 528 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,608 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.