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Strategies for mining fungal natural products

Overview of attention for article published in Journal of Industrial Microbiology & Biotechnology, February 2014
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314 Mendeley
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Title
Strategies for mining fungal natural products
Published in
Journal of Industrial Microbiology & Biotechnology, February 2014
DOI 10.1007/s10295-013-1366-3
Pubmed ID
Authors

Philipp Wiemann, Nancy P Keller

Abstract

Fungi are well known for their ability to produce a multitude of natural products. On the one hand their potential to provide beneficial antibiotics and immunosuppressants has been maximized by the pharmaceutical industry to service the market with cost-efficient drugs. On the other hand identification of trace amounts of known mycotoxins in food and feed samples is of major importance to ensure consumer health and safety. Although several fungal natural products, their biosynthesis and regulation are known today, recent genome sequences of hundreds of fungal species illustrate that the secondary metabolite potential of fungi has been substantially underestimated. Since expression of genes and subsequent production of the encoded metabolites are frequently cryptic or silent under standard laboratory conditions, strategies for activating these hidden new compounds are essential. This review will cover the latest advances in fungal genome mining undertaken to unlock novel products.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 314 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 <1%
Germany 2 <1%
Turkey 1 <1%
Brazil 1 <1%
Taiwan 1 <1%
South Africa 1 <1%
Japan 1 <1%
Denmark 1 <1%
Unknown 303 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 71 23%
Researcher 54 17%
Student > Master 35 11%
Student > Bachelor 32 10%
Student > Doctoral Student 19 6%
Other 51 16%
Unknown 52 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 123 39%
Biochemistry, Genetics and Molecular Biology 61 19%
Chemistry 33 11%
Immunology and Microbiology 6 2%
Pharmacology, Toxicology and Pharmaceutical Science 6 2%
Other 24 8%
Unknown 61 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 May 2017.
All research outputs
#17,700,438
of 25,837,817 outputs
Outputs from Journal of Industrial Microbiology & Biotechnology
#1,318
of 1,629 outputs
Outputs of similar age
#208,087
of 327,847 outputs
Outputs of similar age from Journal of Industrial Microbiology & Biotechnology
#25
of 31 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,629 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 327,847 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.