Title |
Cue Reactivity Is Associated with Duration and Severity of Alcohol Dependence: An fMRI Study
|
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Published in |
PLOS ONE, January 2014
|
DOI | 10.1371/journal.pone.0084560 |
Pubmed ID | |
Authors |
Zsuzsika Sjoerds, Wim van den Brink, Aartjan T. F. Beekman, Brenda W. J. H. Penninx, Dick J. Veltman |
Abstract |
With the progression of substance dependence, drug cue-related brain activation is thought to shift from motivational towards habit pathways. However, a direct association between cue-induced brain activation and dependence duration has not yet been shown. We therefore examined the relationship between alcohol cue-reactivity in the brain, cue-induced subjective craving and alcohol dependence duration and severity. Since alcohol dependence is highly comorbid with depression/anxiety, which may modulate brain responses to alcohol cues, we also examined the relation between comorbid depression/anxiety and cue-reactivity. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Netherlands | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Netherlands | 2 | 2% |
United States | 2 | 2% |
Germany | 2 | 2% |
Canada | 1 | <1% |
Unknown | 104 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 26 | 23% |
Researcher | 15 | 14% |
Student > Master | 12 | 11% |
Student > Bachelor | 11 | 10% |
Professor > Associate Professor | 6 | 5% |
Other | 14 | 13% |
Unknown | 27 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 36 | 32% |
Neuroscience | 15 | 14% |
Medicine and Dentistry | 13 | 12% |
Agricultural and Biological Sciences | 6 | 5% |
Social Sciences | 3 | 3% |
Other | 4 | 4% |
Unknown | 34 | 31% |