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The impact of fish oil and wheat germ oil combination on mineral-bone and inflammatory markers in maintenance hemodialysis patients: a randomized, double-blind, placebo-controlled clinical trial

Overview of attention for article published in Geriatric Nephrology and Urology, June 2017
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Title
The impact of fish oil and wheat germ oil combination on mineral-bone and inflammatory markers in maintenance hemodialysis patients: a randomized, double-blind, placebo-controlled clinical trial
Published in
Geriatric Nephrology and Urology, June 2017
DOI 10.1007/s11255-017-1643-6
Pubmed ID
Authors

Hadeer Zakaria, Tarek M. Mostafa, Gamal A. El-Azab, Ahmed M. Abd El Wahab, Heba Elshahawy, Nagy AH Sayed-Ahmed

Abstract

This study aimed to examine the impact of combined supplementation of fish oil (FO) with antioxidants like wheat germ oil (WGO) on mineral-bone and inflammatory markers in maintenance HD patients. This randomized, double-blind, placebo-controlled trial involved 46 HD patients who were randomly assigned into two groups to receive daily 3000 mg of FO [1053 mg omega-3 fatty acids (ω-3 FAs)] plus 300 mg of WGO [0.765 mg vitamin E] or placebo for 4 months. Blood concentrations of hemoglobin (Hgb), white blood cells, mineral-bone parameters including serum calcium (Ca), phosphorus, calcium-phosphorus product, parathyroid hormone, alkaline phosphatase, and osteoprotegerin and serum concentrations of inflammatory markers including high-sensitivity C-reactive protein, ferritin, and uric acid were measured before and after the intervention. Eighty-seven percentage of patients in each group completed the study. The mean serum Ca levels increased significantly in the supplemented group at the end of study (p = 0.0016), and this increment was also significant as compared to placebo group (p = 0.0418). No significant alterations were observed in the other measured parameters within each group during the study (as p values were >0.05). FO plus WGO supplementation showed beneficial effect on serum Ca levels of HD patients without any statistically significant effect on other mineral-bone and inflammatory markers. Further investigations are required to confirm it.

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Mendeley readers

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The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 14%
Researcher 7 11%
Student > Bachelor 7 11%
Student > Doctoral Student 7 11%
Student > Postgraduate 5 8%
Other 10 16%
Unknown 19 30%
Readers by discipline Count As %
Medicine and Dentistry 14 22%
Nursing and Health Professions 8 13%
Biochemistry, Genetics and Molecular Biology 6 9%
Pharmacology, Toxicology and Pharmaceutical Science 5 8%
Agricultural and Biological Sciences 3 5%
Other 6 9%
Unknown 22 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 July 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Geriatric Nephrology and Urology
#1,233
of 1,493 outputs
Outputs of similar age
#286,713
of 327,487 outputs
Outputs of similar age from Geriatric Nephrology and Urology
#13
of 19 outputs
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