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Posterior cortical atrophy and Alzheimer’s disease: a meta-analytic review of neuropsychological and brain morphometry studies

Overview of attention for article published in Brain Imaging and Behavior, May 2013
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Title
Posterior cortical atrophy and Alzheimer’s disease: a meta-analytic review of neuropsychological and brain morphometry studies
Published in
Brain Imaging and Behavior, May 2013
DOI 10.1007/s11682-013-9236-1
Pubmed ID
Authors

Jorge Alves, José Miguel Soares, Adriana Sampaio, Óscar F. Gonçalves

Abstract

This paper presents the first systematic review and meta-analysis of neuropsychological and brain morphometry studies comparing posterior cortical atrophy (PCA) to typical Alzheimer's disease (tAD). Literature searches were conducted for brain morphometry and neuropsychological studies including a PCA and a tAD group. Compared to healthy controls (HC), PCA patients exhibited significant decreases in temporal, occipital and parietal gray matter (GM) volumes, whereas tAD patients showed extensive left temporal atrophy. Compared to tAD patients, participants with PCA showed greater GM volume reduction in the right occipital gyrus extending to the posterior lobule. In addition, PCA patients showed less GM volume loss in the left parahippocampal gyrus and left hippocampus than tAD patients. PCA patients exhibit significantly greater impairment in Immediate Visuospatial Memory as well as Visuoperceptual and Visuospatial Abilities than patients with tAD. However, tAD patients showed greater impairment in Delayed Auditory/Verbal Memory than patients with PCA. PCA is characterized by significant atrophy of the occipital and parietal regions and severe impairments in visuospatial functioning.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
United Kingdom 1 <1%
Austria 1 <1%
Unknown 103 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 18%
Researcher 13 12%
Student > Master 10 9%
Student > Doctoral Student 9 8%
Other 9 8%
Other 30 28%
Unknown 17 16%
Readers by discipline Count As %
Psychology 31 29%
Medicine and Dentistry 21 20%
Neuroscience 11 10%
Engineering 4 4%
Biochemistry, Genetics and Molecular Biology 3 3%
Other 14 13%
Unknown 23 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2017.
All research outputs
#12,605,103
of 22,751,628 outputs
Outputs from Brain Imaging and Behavior
#423
of 1,153 outputs
Outputs of similar age
#95,890
of 195,591 outputs
Outputs of similar age from Brain Imaging and Behavior
#2
of 13 outputs
Altmetric has tracked 22,751,628 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,153 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 195,591 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.