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Figitumumab in patients with refractory metastatic colorectal cancer previously treated with standard therapies: a nonrandomized, open-label, phase II trial

Overview of attention for article published in Cancer Chemotherapy and Pharmacology, February 2014
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Citations

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Title
Figitumumab in patients with refractory metastatic colorectal cancer previously treated with standard therapies: a nonrandomized, open-label, phase II trial
Published in
Cancer Chemotherapy and Pharmacology, February 2014
DOI 10.1007/s00280-014-2391-2
Pubmed ID
Authors

Carlos R. Becerra, Ramon Salazar, Rocio Garcia-Carbonero, Anne L. Thomas, Federico J. Vázquez-Mazón, James Cassidy, Tim Maughan, Manuel Gallén Castillo, Tim Iveson, Donghua Yin, Stephanie Green, Emily K. Bergsland

Abstract

Figitumumab (CP-751,871) is a human IgG2 monoclonal antibody that binds and down-regulates insulin-like growth factor receptor-1 (IGF-1R) and inhibits activation of this receptor by IGF-1 and IGF-2. This nonrandomized, open-label, single-arm, phase II trial evaluated the antitumor activity and safety of figitumumab in patients with metastatic colorectal cancer that was refractory to ≥2 systemic therapies.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 16%
Student > Bachelor 5 14%
Student > Doctoral Student 4 11%
Other 3 8%
Professor > Associate Professor 3 8%
Other 7 19%
Unknown 9 24%
Readers by discipline Count As %
Medicine and Dentistry 15 41%
Biochemistry, Genetics and Molecular Biology 4 11%
Immunology and Microbiology 3 8%
Agricultural and Biological Sciences 2 5%
Nursing and Health Professions 2 5%
Other 2 5%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 February 2014.
All research outputs
#19,221,261
of 23,815,455 outputs
Outputs from Cancer Chemotherapy and Pharmacology
#2,044
of 2,501 outputs
Outputs of similar age
#234,739
of 311,594 outputs
Outputs of similar age from Cancer Chemotherapy and Pharmacology
#19
of 25 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,501 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,594 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.