Title |
Cloning, sequencing and characterization of the genome of a recombinant norovirus of the rare genotype GII.P7/GII.6 in China
|
---|---|
Published in |
Archives of Virology, March 2017
|
DOI | 10.1007/s00705-017-3325-1 |
Pubmed ID | |
Authors |
Hui Cai, Yongxin Yu, Miao Jin, Yingjie Pan, Shuling Yan, Yongjie Wang |
Abstract |
The genome sequence of a rare recombinant norovirus (NoV) genotype obtained from clinical samples in China was determined using one-step reverse transcription PCR. It was identified as the GII.P7/GII.6 genotype using both phylogenetic and SimPlot analyses. A high degree of variability was observed in the P2 subdomain, especially in the B-loop structure. The recombination breakpoints of all available GII.P7/GII.6 strains were mapped to two different positions within the RdRp region, both of which were at least 40 nt upstream of the overlap of ORF1 and 2. The GII.P7/GII.6 genotype appears to have been circulating in Asia for at least 10 years. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 10 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 3 | 30% |
Researcher | 2 | 20% |
Student > Master | 2 | 20% |
Student > Postgraduate | 1 | 10% |
Unknown | 2 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 3 | 30% |
Biochemistry, Genetics and Molecular Biology | 2 | 20% |
Veterinary Science and Veterinary Medicine | 1 | 10% |
Engineering | 1 | 10% |
Unknown | 3 | 30% |