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Mendeley readers
Attention Score in Context
| Title |
Systematic review of the diagnostic utility of SPECT imaging in dementia
|
|---|---|
| Published in |
European Archives of Psychiatry and Clinical Neuroscience, August 2013
|
| DOI | 10.1007/s00406-013-0426-z |
| Pubmed ID | |
| Authors |
Jing Ming Yeo, Xuxin Lim, Zubair Khan, Suvankar Pal |
| Abstract |
Single-photon emission-computed tomography (SPECT) may potentially contribute to the diagnostic work up of patients with neurodegenerative dementia. This systematic review aims to establish the diagnostic utility of 99mTc-hexamethylpropyleneamine (99mTc-HMPAO) and 99mTc-ethylcysteine dimer SPECT in distinguishing between Alzheimer's disease (AD) and frontotemporal dementia (FTD), AD and vascular dementia (VD), AD and dementia with Lewy bodies (DLB), and AD and normal controls (NC). We searched MEDLINE and Embase databases via OVID for articles from January 1985 to May 2012 and identified additional studies from reviews and references. Of 755 studies, 49 studies met the inclusion and exclusion criteria for this systematic review; AD versus FTD (n=13), AD versus VD (n=18), AD versus DLB (n=5), and AD versus NC (n=18). We compiled relevant data and graded the studies with an internal and external validity criteria checklist. We pooled the studies with a clinical diagnosis and those using 99mTc-HMPAO SPECT in a meta-analysis, calculating the pooled weighted sensitivity, specificity, likelihood ratios, and diagnostic odds ratios using DerSimonian-Laird random-effects model. The pooled weighted sensitivity and specificity of 99mTc-HMPAO-SPECT in distinguishing clinically diagnosed AD from FTD are 79.7 and 79.9%, respectively, AD from VD are 74.5 and 72.4%, AD from DLB are 70.2 and 76.2%, and AD from NC are 76.1 and 85.4%. SPECT does have diagnostic value, particularly in differentiating Alzheimer's disease from frontotemporal dementia and normal controls; however, it should not be used in isolation, rather as an adjunct, and interpreted in the context of clinical information and paraclinical test results. |
Mendeley readers
The data shown below were compiled from readership statistics for 114 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Austria | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Russia | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 109 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 24 | 21% |
| Student > Postgraduate | 14 | 12% |
| Researcher | 13 | 11% |
| Student > Bachelor | 13 | 11% |
| Other | 12 | 11% |
| Other | 20 | 18% |
| Unknown | 18 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 42 | 37% |
| Neuroscience | 12 | 11% |
| Psychology | 8 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 6% |
| Agricultural and Biological Sciences | 5 | 4% |
| Other | 19 | 17% |
| Unknown | 21 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 October 2018.
All research outputs
#7,856,604
of 23,815,455 outputs
Outputs from European Archives of Psychiatry and Clinical Neuroscience
#462
of 1,243 outputs
Outputs of similar age
#66,960
of 199,260 outputs
Outputs of similar age from European Archives of Psychiatry and Clinical Neuroscience
#3
of 14 outputs
Altmetric has tracked 23,815,455 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,243 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 47th percentile – i.e., 47% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 199,260 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.