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Molecular genetics of RecQ helicase disorders

Overview of attention for article published in Cellular and Molecular Life Sciences, June 2007
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

blogs
1 blog
wikipedia
6 Wikipedia pages

Citations

dimensions_citation
110 Dimensions

Readers on

mendeley
76 Mendeley
citeulike
1 CiteULike
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Title
Molecular genetics of RecQ helicase disorders
Published in
Cellular and Molecular Life Sciences, June 2007
DOI 10.1007/s00018-007-7121-z
Pubmed ID
Authors

K. Hanada, I. D. Hickson

Abstract

The RecQ helicases belong to the Superfamily II group of DNA helicases, and are defined by amino acid motifs that show sequence similarity to the catalytic domain of Escherichia coli RecQ. RecQ helicases have crucial roles in the maintenance of genome stability. In humans, there are five RecQ helicases and deficiencies in three of them cause genetic disorders characterised by cancer predisposition, premature aging and/or developmental abnormalities. RecQ helicase-deficient cells exhibit aberrant genetic recombination and/or DNA replication, which result in chromosomal instability and a decreased potential for proliferation. Here, we review the current knowledge of the molecular genetics of RecQ helicases, focusing on the human RecQ helicase disorders and mouse models of these conditions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 3%
United Kingdom 1 1%
India 1 1%
Canada 1 1%
Unknown 71 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 33%
Researcher 11 14%
Professor > Associate Professor 6 8%
Student > Bachelor 6 8%
Student > Master 4 5%
Other 12 16%
Unknown 12 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 37 49%
Biochemistry, Genetics and Molecular Biology 14 18%
Medicine and Dentistry 7 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 1%
Unspecified 1 1%
Other 2 3%
Unknown 14 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2021.
All research outputs
#2,842,694
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#431
of 4,151 outputs
Outputs of similar age
#5,636
of 58,843 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#4
of 33 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 58,843 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.