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Mendeley readers
Attention Score in Context
| Title |
RETRACTED ARTICLE: Strategies for efficient production of heterologous proteins in Escherichia coli
|
|---|---|
| Published in |
Applied Microbiology and Biotechnology, January 2005
|
| DOI | 10.1007/s00253-004-1814-0 |
| Pubmed ID | |
| Authors |
S. Jana, J. K. Deb |
| Abstract |
In recent years, the number of recombinant proteins used for therapeutic applications has increased dramatically. Production of these proteins has a remarkable demand in the market. Escherichia coli offers a means for the rapid and economical production of recombinant proteins. These advantages, coupled with a wealth of biochemical and genetic knowledge, have enabled the production of such economically therapeutic proteins such as insulin and bovine growth hormone. These demands have driven the development of a variety of strategies for achieving high-level expression of protein, particularly involving several aspects such as expression vectors design, gene dosage, promoter strength (transcriptional regulation), mRNA stability, translation initiation and termination (translational regulation), host design considerations, codon usage, and fermentation factors available for manipulating the expression conditions, which are the major challenges is obtaining the high yield of protein at low cost. |
Mendeley readers
The data shown below were compiled from readership statistics for 552 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 6 | 1% |
| United Kingdom | 4 | <1% |
| United States | 3 | <1% |
| Denmark | 3 | <1% |
| Netherlands | 2 | <1% |
| Mexico | 2 | <1% |
| Italy | 1 | <1% |
| Uruguay | 1 | <1% |
| Malaysia | 1 | <1% |
| Other | 7 | 1% |
| Unknown | 522 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 124 | 22% |
| Researcher | 100 | 18% |
| Student > Master | 81 | 15% |
| Student > Bachelor | 77 | 14% |
| Student > Postgraduate | 26 | 5% |
| Other | 74 | 13% |
| Unknown | 70 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 264 | 48% |
| Biochemistry, Genetics and Molecular Biology | 101 | 18% |
| Chemistry | 35 | 6% |
| Engineering | 27 | 5% |
| Immunology and Microbiology | 12 | 2% |
| Other | 36 | 7% |
| Unknown | 77 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 25. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 October 2023.
All research outputs
#1,393,661
of 24,119,703 outputs
Outputs from Applied Microbiology and Biotechnology
#75
of 8,034 outputs
Outputs of similar age
#2,995
of 145,226 outputs
Outputs of similar age from Applied Microbiology and Biotechnology
#2
of 68 outputs
Altmetric has tracked 24,119,703 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,034 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 145,226 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.