↓ Skip to main content

Shared Dysregulation of Homeostatic Brain-Body Pathways in Depression and Type 2 Diabetes

Overview of attention for article published in Current Diabetes Reports, August 2017
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

policy
1 policy source
twitter
4 X users

Citations

dimensions_citation
24 Dimensions

Readers on

mendeley
163 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Shared Dysregulation of Homeostatic Brain-Body Pathways in Depression and Type 2 Diabetes
Published in
Current Diabetes Reports, August 2017
DOI 10.1007/s11892-017-0923-y
Pubmed ID
Authors

Claire J. Hoogendoorn, Juan F. Roy, Jeffrey S. Gonzalez

Abstract

The purpose of this review is to provide an overview of shared dysregulation of the hypothalamic-pituitary-adrenal (HPA) and brain-gut-microbiome (BGM) axes associated with depression and type 2 diabetes (T2D). Clinical implications and future research are also discussed. Both depression and T2D are associated with dysregulation of the HPA and BGM axes. These pathways regulate immune function, glucose metabolism, and sleep, which are altered in both illnesses. Dysregulation of homeostatic brain-body pathways may be positively influenced through different therapeutic actions, including psychotherapy, healthy eating, physical activity, sleep promotion, and certain anti-inflammatory or antidepressant medications. While the causal nature of the relationship between depression and T2D remains unclear, these conditions share dysregulation of homeostatic brain-body pathways that are central to mental and physical health. Better understanding of this dysregulation may provide opportunities for interventions that could benefit both conditions. Future research should examine the additive burden of depression and T2D on HPA and BGM dysregulation and better differentiate depression from emotional distress.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 163 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 163 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 27 17%
Student > Bachelor 25 15%
Researcher 17 10%
Student > Ph. D. Student 15 9%
Student > Doctoral Student 8 5%
Other 22 13%
Unknown 49 30%
Readers by discipline Count As %
Medicine and Dentistry 26 16%
Nursing and Health Professions 17 10%
Neuroscience 14 9%
Psychology 14 9%
Agricultural and Biological Sciences 11 7%
Other 28 17%
Unknown 53 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2019.
All research outputs
#6,205,257
of 24,473,185 outputs
Outputs from Current Diabetes Reports
#304
of 1,041 outputs
Outputs of similar age
#83,561
of 291,623 outputs
Outputs of similar age from Current Diabetes Reports
#8
of 36 outputs
Altmetric has tracked 24,473,185 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,041 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.9. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,623 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.