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X Demographics
Mendeley readers
| Title |
Update to the study protocol for a randomized controlled trial comparing mindfulness-based cognitive therapy with maintenance anti-depressant treatment depressive relapse/recurrence: the PREVENT trial
|
|---|---|
| Published in |
Trials, June 2014
|
| DOI | 10.1186/1745-6215-15-217 |
| Pubmed ID | |
| Authors |
Willem Kuyken, Sarah Byford, Richard Byng, Tim Dalgleish, Glyn Lewis, Rod Taylor, Edward R Watkins, Rachel Hayes, Paul Lanham, David Kessler, Nicola Morant, Alison Evans |
| Abstract |
Depression is a common and distressing mental health problem that is responsible for significant individual disability and cost to society. Medication and psychological therapies are effective for treating depression and maintenance antidepressants (m-ADM) can prevent relapse, whereas, r psychological help can help them recover from depression in the longterm. A recently developed treatment, mindfulness-based cognitive therapy (MBCT), shows potential as a brief group program for people with recurring depression..This trial asks the policy research question; is MBCT with support to taper/discontinue antidepressant medication (MBCT-TS) superior to m-ADM in terms of: a primary outcome of preventing depressive relapse/recurrence over 24 months; and secondary outcomes of (a) depression free days, (b) residual depressive symptoms, (c) antidepressant medication (ADM) usage, (d) (d) psychiatric and medical co-morbidity, (e) quality of life, and (f) cost effectiveness? An explanatory research question also asks whether an increase in mindfulness skills is the key mechanism of change.The design is a single-blind, parallel randomized controlled trial examining MBCT-TS versus m-ADM with an embedded process study. To answer the main policy research question the proposed trial compares MBCT-TS with m-ADM for patients with recurrent depression. Four hundred and twenty patients with recurrent major depressive disorder in full or partial remission will be recruited through primary care. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 33% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 237 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 2 | <1% |
| United States | 1 | <1% |
| Unknown | 234 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 36 | 15% |
| Student > Master | 34 | 14% |
| Student > Ph. D. Student | 28 | 12% |
| Student > Doctoral Student | 19 | 8% |
| Student > Bachelor | 19 | 8% |
| Other | 59 | 25% |
| Unknown | 42 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 82 | 35% |
| Medicine and Dentistry | 39 | 16% |
| Nursing and Health Professions | 14 | 6% |
| Unspecified | 14 | 6% |
| Social Sciences | 10 | 4% |
| Other | 29 | 12% |
| Unknown | 49 | 21% |