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Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury

Overview of attention for article published in Cardiovascular Research, June 2014
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42 Mendeley
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Title
Leucocyte expression of complement C5a receptors exacerbates infarct size after myocardial reperfusion injury
Published in
Cardiovascular Research, June 2014
DOI 10.1093/cvr/cvu153
Pubmed ID
Authors

Vince C. De Hoog, Leo Timmers, Amerik Van Duijvenvoorde, Saskia C. A. De Jager, Ben J. Van Middelaar, Mirjam B. Smeets, Trent M. Woodruff, Pieter A. Doevendans, Gerard Pasterkamp, C. Erik Hack, Dominique P.V. De Kleijn

Abstract

Early reperfusion is mandatory for the treatment of acute myocardial infarction. This process, however, also induces additional loss of viable myocardium, called ischemia-reperfusion (IR) injury. Complement activation plays an important role in IR injury, partly through binding of C5a to its major receptor (C5aR). We investigated the role of C5aR on infarct size and cardiac function in a model for myocardial IR injury.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Netherlands 1 2%
Canada 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 26%
Researcher 8 19%
Student > Bachelor 6 14%
Student > Master 5 12%
Professor 2 5%
Other 4 10%
Unknown 6 14%
Readers by discipline Count As %
Medicine and Dentistry 19 45%
Agricultural and Biological Sciences 9 21%
Environmental Science 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 2 5%
Unknown 9 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2014.
All research outputs
#16,220,603
of 25,630,321 outputs
Outputs from Cardiovascular Research
#10
of 61 outputs
Outputs of similar age
#132,682
of 243,391 outputs
Outputs of similar age from Cardiovascular Research
#1
of 4 outputs
Altmetric has tracked 25,630,321 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 61 research outputs from this source. They receive a mean Attention Score of 1.0. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,391 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them