Hypertrophic cardiomyopathy mutations Y115H and E497D disrupt the folded-back state of human β-cardiac myosin allosterically
Preprint in bioRxiv (March 2024)
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Structure of mavacamten-free human cardiac thick filaments within the sarcomere by cryoelectron tomography
Article in Proceedings of the National Academy of Sciences of the United States of America (February 2024)
Mavacamten, a precision medicine for hypertrophic cardiomyopathy: From a motor protein to patients
Article in Science Advances (July 2023)