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An assessment of the relationship between clinical utility and predictive ability measures and the impact of mean risk in the population

Overview of attention for article published in BMC Medical Research Methodology, July 2014
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Title
An assessment of the relationship between clinical utility and predictive ability measures and the impact of mean risk in the population
Published in
BMC Medical Research Methodology, July 2014
DOI 10.1186/1471-2288-14-86
Pubmed ID
Authors

Kevin McGeechan, Petra Macaskill, Les Irwig, Patrick MM Bossuyt

Abstract

Measures of clinical utility (net benefit and event free life years) have been recommended in the assessment of a new predictor in a risk prediction model. However, it is not clear how they relate to the measures of predictive ability and reclassification, such as the c-statistic and Net Reclassification Improvement (NRI), or how these measures are affected by differences in mean risk between populations when a fixed cutpoint to define high risk is assumed.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 25%
Student > Bachelor 4 17%
Researcher 3 13%
Professor > Associate Professor 2 8%
Professor 2 8%
Other 4 17%
Unknown 3 13%
Readers by discipline Count As %
Medicine and Dentistry 12 50%
Engineering 2 8%
Nursing and Health Professions 1 4%
Computer Science 1 4%
Mathematics 1 4%
Other 4 17%
Unknown 3 13%