Computational Modeling of Drugs Against Alzheimer’s Disease

Chapter 1 Alzheimer’s Disease Therapy: Present and Future Molecules

Chapter 2 Recent Advances in Computational Approaches for Designing Potential Anti-Alzheimer’s Agents

Chapter 3 Computer-Aided Drug Design Approaches to Study Key Therapeutic Targets in Alzheimer’s Disease

Chapter 4 Virtual Screening in the Search of New and Potent Anti-Alzheimer Agents

Chapter 5 Molecular Field Topology Analysis (MFTA) in the Design of Neuroprotective Compounds

Chapter 6 Galantamine Derivatives as Acetylcholinesterase Inhibitors: Docking, Design, Synthesis, and Inhibitory Activity

Chapter 7 Modeling of BACE-1 Inhibitors as Anti-Alzheimer’s Agents

Chapter 8 Design of Anti-Alzheimer’s Disease Agents Focusing on a Specific Interaction with Target Biomolecules

Chapter 9 Molecular Docking and Molecular Dynamics Simulation to Evaluate Compounds That Avoid the Amyloid Beta 1-42 Aggregation

Chapter 10 In Silico Strategies to Design Small Molecules to Study Beta-Amyloid Aggregation

Chapter 11 Computational Approaches to Understand Cleavage Mechanism of Amyloid Beta (A β ) Peptide

Chapter 12 Computational Modeling of Gamma-Secretase Inhibitors as Anti-Alzheimer Agents

Chapter 13 Molecular Modeling of Tau Proline-Directed Protein Kinase (PDPK) Inhibitors

Chapter 14 Computational Modelling of Kinase Inhibitors as Anti-Alzheimer Agents

Chapter 15 Computational Modeling of Drugs for Alzheimer’s Disease: Design of Serotonin 5-HT 6 Antagonists

Chapter 16 Computational Modeling of Diagnostic Imaging Agents for Alzheimer’s Disease: Molecular Imaging Agents for the In Vivo Detection of Amyloid Plaques in Alzheimer’s Disease

Chapter 17 Computational Approaches for Therapeutic Application of Natural Products in Alzheimer’s Disease

Chapter 18 In Silico Studies Applied to Natural Products with Potential Activity Against Alzheimer’s Disease

Chapter 19 Computational Modeling of Multi-target-Directed Inhibitors Against Alzheimer’s Disease

Chapter 20 Neuropharmacology in Flux: Molecular Modeling Tools for Understanding Protein Conformational Shifts in Alzheimer’s Disease and Related Disorders

Chapter 21 Computational Nanotechnology: A Tool for Screening Therapeutic Nanomaterials Against Alzheimer’s Disease