Title |
Electronic bypass of spinal lesions: activation of lower motor neurons directly driven by cortical neural signals
|
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Published in |
Journal of NeuroEngineering and Rehabilitation, July 2014
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DOI | 10.1186/1743-0003-11-107 |
Pubmed ID | |
Authors |
Yan Li, Monzurul Alam, Shanshan Guo, KH Ting, Jufang He |
Abstract |
Lower motor neurons in the spinal cord lose supraspinal inputs after complete spinal cord injury, leading to a loss of volitional control below the injury site. Extensive locomotor training with spinal cord stimulation can restore locomotion function after spinal cord injury in humans and animals. However, this locomotion is non-voluntary, meaning that subjects cannot control stimulation via their natural "intent". A recent study demonstrated an advanced system that triggers a stimulator using forelimb stepping electromyographic patterns to restore quadrupedal walking in rats with spinal cord transection. However, this indirect source of "intent" may mean that other non-stepping forelimb activities may false-trigger the spinal stimulator and thus produce unwanted hindlimb movements. |
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Mendeley readers
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