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HPV and Anal Cancer in HIV-Infected Individuals: A Review

Overview of attention for article published in Current HIV/AIDS Reports, July 2014
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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2 policy sources
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1 X user

Citations

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77 Dimensions

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128 Mendeley
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Title
HPV and Anal Cancer in HIV-Infected Individuals: A Review
Published in
Current HIV/AIDS Reports, July 2014
DOI 10.1007/s11904-014-0224-x
Pubmed ID
Authors

Maarten F. Schim van der Loeff, Sofie H. Mooij, Oliver Richel, Henry J. C. de Vries, Jan M. Prins

Abstract

HIV infection is one of the strongest risk factors for anal squamous cell cancer (ASCC). Most ASCC are caused by HPV, and most HPV-associated ASCC are caused by HPV-16. Anal HPV infections are very common in men who have sex with men (MSM), and nearly universal among HIV-infected MSM. High-grade anal intraepithelial neoplasia (HGAIN), the precursor for ASCC, is present in about 30 % of HIV+ MSM, but neither the progression rate to ASCC nor the regression rate are known. The incidence rate of ASCC among HIV-infected people has risen in the first decade after cART became available, but appears to be plateauing recently. Anal cytology has poor sensitivity and specificity. High resolution anoscopy (HRA) is advocated by some as a screening tool in high-risk groups, but is cumbersome and time-consuming and it is unknown whether HRA followed by treatment of HGAIN prevents ASCC. More research is needed on progression and regression rates of HGAIN, on effective therapy of HGAIN, and on biomarkers that predict HGAIN or anal cancer. HPV vaccination and earlier start of cART may prevent most anal cancers in the long run.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 128 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
Italy 1 <1%
Unknown 125 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 16%
Researcher 20 16%
Student > Master 14 11%
Student > Bachelor 14 11%
Student > Doctoral Student 10 8%
Other 20 16%
Unknown 30 23%
Readers by discipline Count As %
Medicine and Dentistry 57 45%
Agricultural and Biological Sciences 10 8%
Biochemistry, Genetics and Molecular Biology 7 5%
Social Sciences 6 5%
Nursing and Health Professions 4 3%
Other 12 9%
Unknown 32 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 July 2017.
All research outputs
#4,506,995
of 22,758,963 outputs
Outputs from Current HIV/AIDS Reports
#97
of 429 outputs
Outputs of similar age
#44,546
of 227,670 outputs
Outputs of similar age from Current HIV/AIDS Reports
#3
of 14 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 429 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,670 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.