Title |
Probiotics for pediatric antibiotic-associated diarrhea: a meta-analysis of randomized placebo-controlled trials
|
---|---|
Published in |
Canadian Medical Association Journal, August 2006
|
DOI | 10.1503/cmaj.051603 |
Pubmed ID | |
Authors |
Bradley C Johnston, Alison L Supina, Sunita Vohra |
Abstract |
Antibiotic treatment is known to disturb gastrointestinal microflora, which results in a range of clinical symptoms--most notably, diarrhea. This is especially important in children, for whom antibiotics are prescribed frequently. Although meta-analyses have been conducted to evaluate the ability of probiotics to prevent antibiotic-induced diarrhea in the general population, little is known about which probiotic strains and doses might be of most benefit to children. Our objective in this study was to assess the efficacy of probiotics (of any specified strain or dose) for the prevention of antibiotic-associated diarrhea in children and to assess adverse events associated with the use of probiotics when coadministered with antibiotics to children. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Canada | 1 | <1% |
Unknown | 173 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 31 | 18% |
Student > Master | 24 | 14% |
Other | 22 | 13% |
Student > Bachelor | 14 | 8% |
Student > Ph. D. Student | 14 | 8% |
Other | 33 | 19% |
Unknown | 38 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 58 | 33% |
Agricultural and Biological Sciences | 30 | 17% |
Biochemistry, Genetics and Molecular Biology | 8 | 5% |
Nursing and Health Professions | 7 | 4% |
Immunology and Microbiology | 7 | 4% |
Other | 25 | 14% |
Unknown | 41 | 23% |