Title |
Neural substrates of impulsive decision making modulated by modafinil in alcohol-dependent patients
|
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Published in |
Psychological Medicine, March 2014
|
DOI | 10.1017/s0033291714000312 |
Pubmed ID | |
Authors |
L. Schmaal, A. E. Goudriaan, L. Joos, G. Dom, T. Pattij, W. van den Brink, D. J. Veltman |
Abstract |
Impulsive decision making is a hallmark of frequently occurring addiction disorders including alcohol dependence (AD). Therefore, ameliorating impulsive decision making is a promising target for the treatment of AD. Previous studies have shown that modafinil enhances cognitive control functions in various psychiatric disorders. However, the effects of modafinil on delay discounting and its underlying neural correlates have not been investigated as yet. The aim of the current study was to investigate the effects of modafinil on neural correlates of impulsive decision making in abstinent AD patients and healthy control (HC) subjects. |
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Other | 8 | 7% |
Unknown | 41 | 35% |