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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Pathologic complete response to neoadjuvant cisplatin in BRCA1-positive breast cancer patients
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, August 2014
|
| DOI | 10.1007/s10549-014-3100-x |
| Pubmed ID | |
| Authors |
T. Byrski, T. Huzarski, R. Dent, E. Marczyk, M. Jasiowka, J. Gronwald, J. Jakubowicz, C. Cybulski, R. Wisniowski, D. Godlewski, J. Lubinski, S. A. Narod |
| Abstract |
The aim of this study is to estimate the frequency of pathologic complete response (pCR) after neoadjuvant treatment with cisplatin chemotherapy in women with breast cancer and a BRCA1 mutation. One hundred and seven women with breast cancer and a BRCA1 mutation, who were diagnosed with stage I to III breast cancer between December 2006 and June 2014, were treated with cisplatin 75 mg/m(2) every 3 weeks for four cycles, followed by mastectomy and conventional chemotherapy. Information was collected on clinical stage, grade, hormone receptor status, and Her2neu status prior to treatment. pCR was determined by review of surgical specimens. One hundred and seven patients were enrolled in the study, including 93 patients who were treated for first primary breast cancer and 14 patients who had previously received treatment for a prior cancer. A pCR was observed in 65 of the 107 patients (61 %). Platinum-based chemotherapy is effective in a high proportion of patients with BRCA1-associated breast cancer. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | <1% |
| Belgium | 1 | <1% |
| Denmark | 1 | <1% |
| Russia | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 130 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 15% |
| Student > Bachelor | 20 | 15% |
| Researcher | 18 | 13% |
| Other | 14 | 10% |
| Student > Doctoral Student | 9 | 7% |
| Other | 23 | 17% |
| Unknown | 31 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 45 | 33% |
| Biochemistry, Genetics and Molecular Biology | 22 | 16% |
| Agricultural and Biological Sciences | 13 | 10% |
| Chemistry | 4 | 3% |
| Chemical Engineering | 2 | 1% |
| Other | 15 | 11% |
| Unknown | 34 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2014.
All research outputs
#14,198,795
of 22,760,687 outputs
Outputs from Breast Cancer Research and Treatment
#3,077
of 4,652 outputs
Outputs of similar age
#121,040
of 234,981 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#30
of 59 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,652 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 234,981 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 59 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.