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Blood lead and preeclampsia: A meta-analysis and review of implications

Overview of attention for article published in Environmental Research, September 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

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4 news outlets
policy
1 policy source
twitter
7 X users
facebook
3 Facebook pages

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123 Mendeley
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Title
Blood lead and preeclampsia: A meta-analysis and review of implications
Published in
Environmental Research, September 2017
DOI 10.1016/j.envres.2017.09.014
Pubmed ID
Authors

Arthur E. Poropat, Mark A.S. Laidlaw, Bruce Lanphear, Andrew Ball, Howard W. Mielke

Abstract

Multiple cross-sectional studies suggest that there is an association between blood lead and preeclampsia. We performed a systematic review and meta-analysis to summarize information on the association between preeclampsia and lead poisoning. Searches of Medline, Web of Science, Scopus, Pubmed, Science Direct and ProQuest (dissertations and theses) identified 2089 reports, 46 of which were downloaded after reviewing the abstracts, and 11 studies were evaluated as meeting the selection criteria. Evaluation using the ROBINS-I template (Sterne, et al., 2016), indicated moderate risk of bias in all studies. We found that blood lead concentrations were significantly and substantially associated with preeclampsia (k = 12; N = 6069; Cohen's d = 1.26; odds ratio = 9.81; odds ratio LCL = 8.01; odds ratio UCL = 12.02; p = 0.005). Eliminating one study produced a homogeneous meta-analysis and stronger estimates, despite the remaining studies coming from eight separate countries and having countervailing risks of bias. Blood lead concentrations in pregnant women are a major risk factor for preeclampsia, with an increase of 1μg/dL associated with a 1.6% increase in likelihood of preeclampsia, which appears to be the strongest risk factor for preeclampsia yet reported. Pregnant women with historical lead exposure should routinely have blood lead concentrations tested, especially after mid-term. Women with concentrations higher than 5μg/dL should be actively monitored for preeclampsia and be advised to take prophylactic calcium supplementation. All pregnant women should be advised to actively avoid lead exposure.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 123 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 19 15%
Researcher 9 7%
Student > Ph. D. Student 8 7%
Student > Bachelor 8 7%
Student > Doctoral Student 7 6%
Other 24 20%
Unknown 48 39%
Readers by discipline Count As %
Medicine and Dentistry 21 17%
Nursing and Health Professions 7 6%
Agricultural and Biological Sciences 6 5%
Social Sciences 5 4%
Environmental Science 5 4%
Other 26 21%
Unknown 53 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 44. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2022.
All research outputs
#947,312
of 25,382,440 outputs
Outputs from Environmental Research
#474
of 7,953 outputs
Outputs of similar age
#19,326
of 325,640 outputs
Outputs of similar age from Environmental Research
#10
of 114 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,953 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.5. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,640 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.