@Balciunas_Lab We could perform clonal analysis with I-SceI based lines: https://t.co/Jk3AgKFerk Here, 4-OHT concentration and recombination needed to be reproducible between animals. With Tol2, the multiple loci lead to high variability between siblings,
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Different Dev. Histories of Beta-Cells Generate Functional & Proliferative Heterogeneity during Islet Growth https://t.co/2WYWMNmkjW https://t.co/pj0iODvaCF
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Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth Nat Commun 0922 https://t.co/4rR0eQBVBQ ...we adapted the Brainbow methodology2, 28 for studying beta-cells, henceforth called beta-bow.
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RT @GavBew: Super elegant use of genetic tracing to demonstrate beta-cell functional heterogeneity by age and origin https://t.co/t3vy9z0bx…