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Time-of-flight ion mobility spectrometry in combination with laser-induced fluorescence detection system

Overview of attention for article published in Analytical & Bioanalytical Chemistry, August 2017
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Title
Time-of-flight ion mobility spectrometry in combination with laser-induced fluorescence detection system
Published in
Analytical & Bioanalytical Chemistry, August 2017
DOI 10.1007/s00216-017-0584-3
Pubmed ID
Authors

Florian Uteschil, Andriy Kuklya, Klaus Kerpen, Robert Marks, Ursula Telgheder

Abstract

A laser-induced fluorescence (LIF) was used as a complimentary detection system for time-of-flight ion mobility spectrometry (TOF-IMS). A LIF detection system is potentially faster than a conventional electrometer detector and can provide additional (to usual for IMS drift time) analytical information, namely wavelength of fluorescence maxima and fluorescence lifetime. Therefore, better discrimination ability can be expected. Additionally, the combination of IMS and LIF operates at atmospheric pressure. This allows fluorescence measurements of specified ions and ion clusters, which would not survive in a mass spectrometer. An IMS drift cell of open design with both the electrometer and LIF detectors was designed. The feasibility of IMS-LIF was demonstrated on the example of the Xanthene dye Rhodamine 6G (R6G). Electrospray was used as an ionization source. The release and desolvation of R6G ions from the electrospray with following IMS-LIF analysis were demonstrated. The effects of experimental parameters (e.g., ion gate and drift voltages, distance to ESI emitter) are demonstrated and discussed. The obtained results are promising enough to ensure the potential of LIF as a complimentary/alternative detection system for time-of-flight ion mobility spectrometry.

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X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 50%
Other 1 8%
Lecturer > Senior Lecturer 1 8%
Student > Ph. D. Student 1 8%
Professor 1 8%
Other 0 0%
Unknown 2 17%
Readers by discipline Count As %
Chemistry 5 42%
Engineering 2 17%
Physics and Astronomy 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Unknown 3 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2017.
All research outputs
#16,725,651
of 25,382,440 outputs
Outputs from Analytical & Bioanalytical Chemistry
#5,260
of 9,619 outputs
Outputs of similar age
#196,580
of 324,511 outputs
Outputs of similar age from Analytical & Bioanalytical Chemistry
#51
of 158 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,619 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,511 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.