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Endoscopic submucosal dissection for undifferentiated-type early gastric cancer: short- and long-term outcomes

Overview of attention for article published in Surgical Endoscopy, October 2017
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Title
Endoscopic submucosal dissection for undifferentiated-type early gastric cancer: short- and long-term outcomes
Published in
Surgical Endoscopy, October 2017
DOI 10.1007/s00464-017-5892-3
Pubmed ID
Authors

Hye Kyung Jeon, Seong Jun Lee, Gwang Ha Kim, Do Youn Park, Bong Eun Lee, Geun Am Song

Abstract

Application of endoscopic submucosal dissection (ESD) for undifferentiated-type early gastric cancers (EGCs) remains controversial owing to limited data regarding long-term outcomes. We aimed to evaluate the feasibility of ESD for undifferentiated-type EGCs that meet the expanded criteria (EC). We performed a retrospective analysis of 66 patients who underwent ESD for undifferentiated-type EGC between January 2005 and December 2014. We evaluated the rates of en bloc, complete, and curative resections along with overall survival (OS), disease-specific survival (DSS), and recurrence-free survival (RFS). Of the 66 patients, the EC group included 38 patients and the beyond-EC group included 28 patients. The overall rates of en bloc, complete, and curative resection of the 66 lesions were 92.4% (61/66), 65.2% (43/66), and 48.5% (32/66), respectively. Of the 34 patients with non-curative resection, 18 underwent additional surgery. Local remnant cancer was detected in 1 patient (1/18, 5.6%), and none of the 18 patients had lymph node metastasis. On multivariate analysis, tumors > 2 cm [odd ratio (OR) 6.183, 95% confidence interval (CI) 1.279-29.880, p = 0.023) and submucosal invasion depth (OR 6.226, 95% CI 1.881-20.606, p = 0.003) were independent predictors of incomplete resection. All 26 patients with more than 1 year of follow-up after curative resection survived without any evidence of local or distant recurrences over a median follow-up period of 36 months. The OS, DSS, and RFS rates of patients with curative ESD were 93.8, 100, and 100%, respectively. ESD may have favorable long-term outcomes in patients with undifferentiated-type EGC after curative resection.

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Geographical breakdown

Country Count As %
Brazil 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Professor 2 13%
Other 2 13%
Student > Doctoral Student 2 13%
Student > Bachelor 2 13%
Researcher 2 13%
Other 5 33%
Readers by discipline Count As %
Medicine and Dentistry 11 73%
Agricultural and Biological Sciences 1 7%
Biochemistry, Genetics and Molecular Biology 1 7%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2017.
All research outputs
#18,574,814
of 23,006,268 outputs
Outputs from Surgical Endoscopy
#4,793
of 6,101 outputs
Outputs of similar age
#250,658
of 327,016 outputs
Outputs of similar age from Surgical Endoscopy
#99
of 112 outputs
Altmetric has tracked 23,006,268 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,101 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
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We're also able to compare this research output to 112 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.