Title |
Evidence that bisphenol A (BPA) can be accurately measured without contamination in human serum and urine, and that BPA causes numerous hazards from multiple routes of exposure
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Published in |
Molecular & Cellular Endocrinology, October 2014
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DOI | 10.1016/j.mce.2014.09.028 |
Pubmed ID | |
Authors |
Frederick S. vom Saal, Wade V. Welshons |
Abstract |
There is extensive evidence that bisphenol A (BPA) is related to a wide range of adverse health effects based on both human and experimental animal studies. However, a number of regulatory agencies have ignored all hazard findings. Reports of high levels of unconjugated (bioactive) serum BPA in dozens of human biomonitoring studies have also been rejected based on the prediction that the findings are due to assay contamination and that virtually all ingested BPA is rapidly converted to inactive metabolites. NIH and industry-sponsored round robin studies have demonstrated that serum BPA can be accurately assayed without contamination, while the FDA lab has acknowledged uncontrolled assay contamination. In reviewing the published BPA biomonitoring data, we find that assay contamination is, in fact, well controlled in most labs, and cannot be used as the basis for discounting evidence that significant and virtually continuous exposure to BPA must be occurring from multiple sources. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 38% |
Unknown | 5 | 63% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 50% |
Scientists | 2 | 25% |
Science communicators (journalists, bloggers, editors) | 1 | 13% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | <1% |
Unknown | 134 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 27 | 20% |
Student > Master | 23 | 17% |
Student > Bachelor | 18 | 13% |
Researcher | 11 | 8% |
Student > Postgraduate | 9 | 7% |
Other | 19 | 14% |
Unknown | 28 | 21% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 18 | 13% |
Medicine and Dentistry | 17 | 13% |
Environmental Science | 16 | 12% |
Agricultural and Biological Sciences | 13 | 10% |
Chemistry | 13 | 10% |
Other | 23 | 17% |
Unknown | 35 | 26% |