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The anti-adhesive mode of action of a purified mushroom (Lentinus edodes) extract with anticaries and antigingivitis properties in two oral bacterial pathogens

Overview of attention for article published in BMC Complementary Medicine and Therapies, February 2014
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Title
The anti-adhesive mode of action of a purified mushroom (Lentinus edodes) extract with anticaries and antigingivitis properties in two oral bacterial pathogens
Published in
BMC Complementary Medicine and Therapies, February 2014
DOI 10.1186/1472-6882-14-75
Pubmed ID
Authors

Caterina Signoretto, Anna Marchi, Anna Bertoncelli, Gloria Burlacchini, Adele Papetti, Carla Pruzzo, Egija Zaura, Peter Lingström, Itzhak Ofek, Jonathan Pratten, David A Spratt, Michael Wilson, Pietro Canepari

Abstract

In previous works we have shown that a low-molecular-mass (LMM) fraction from mushroom (Lentinus edodes) homogenate interferes with binding of Streptococcus mutans to hydroxyapatite and Prevotella intermedia to gingival cells. Additionally, inhibition of biofilm formation of both odonto- and periodonto-pathogenic bacteria and detachment from preformed biofilms have been described for this compound. Further purification of mushroom extract has been recently achieved and a sub-fraction (i.e. # 5) has been identified as containing the majority of the mentioned biological activities. The aim of this study was to characterise the bacterial receptors for the purified mushroom sub-fraction #5 in order to better elucidate the mode of action of this compound when interfering with bacterial adhesion to host surfaces or with bacteria-bacteria interactions in the biofilm state.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Unknown 54 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 15%
Lecturer 5 9%
Researcher 5 9%
Student > Ph. D. Student 5 9%
Student > Bachelor 4 7%
Other 9 16%
Unknown 19 35%
Readers by discipline Count As %
Medicine and Dentistry 13 24%
Agricultural and Biological Sciences 6 11%
Immunology and Microbiology 6 11%
Pharmacology, Toxicology and Pharmaceutical Science 3 5%
Social Sciences 1 2%
Other 3 5%
Unknown 23 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2014.
All research outputs
#18,380,628
of 22,766,595 outputs
Outputs from BMC Complementary Medicine and Therapies
#2,504
of 3,622 outputs
Outputs of similar age
#162,769
of 223,263 outputs
Outputs of similar age from BMC Complementary Medicine and Therapies
#76
of 93 outputs
Altmetric has tracked 22,766,595 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,622 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 223,263 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.