Title |
FiO2 predicts outcome in infants with respiratory syncytial virus‐induced acute respiratory distress syndrome
|
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Published in |
Pediatric Pulmonology, December 2013
|
DOI | 10.1002/ppul.22974 |
Pubmed ID | |
Authors |
Kiry M. Schene, Elske van den Berg, Roelie M. Wösten‐van Asperen, Rick R. van Rijn, Albert P. Bos, Job B.M. van Woensel |
Abstract |
Respiratory syncytial virus (RSV) infection can progress to acute respiratory distress syndrome (ARDS) in infants. ARDS is a life-threatening condition that is characterized by severe hypoxemia, defined as PaO2 /FiO2 ratio <300 mmHg. This ratio is used in many trials as the sole oxygenation criterion for ARDS. Recently, however, it has been shown in adults with ARDS that FiO2 , independently of the PaO2 /FiO2 ratio predicts mortality. Because epidemiology and outcome of ARDS differ strongly between children and adults, we determined if FiO2 on admission (baseline FiO2 ) independently predicted the duration of mechanical ventilation (MV) and length of stay (LOS) in the pediatric intensive care unit (PICU) in infants with RSV-induced ARDS. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 56 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 20% |
Student > Ph. D. Student | 8 | 14% |
Researcher | 6 | 11% |
Student > Postgraduate | 5 | 9% |
Student > Bachelor | 3 | 5% |
Other | 9 | 16% |
Unknown | 14 | 25% |
Readers by discipline | Count | As % |
---|---|---|
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Nursing and Health Professions | 6 | 11% |
Engineering | 3 | 5% |
Immunology and Microbiology | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 4% |
Other | 9 | 16% |
Unknown | 13 | 23% |