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Selection, resistance risk assessment, and reversion toward susceptibility of pyriproxyfen in Musca domestica L.

Overview of attention for article published in Parasitology Research, November 2014
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Title
Selection, resistance risk assessment, and reversion toward susceptibility of pyriproxyfen in Musca domestica L.
Published in
Parasitology Research, November 2014
DOI 10.1007/s00436-014-4206-0
Pubmed ID
Authors

Rizwan Mustafa Shah, Naeem Abbas, Sarfraz Ali Shad, Ashfaq Ahmad Sial

Abstract

Pyriproxyfen, a juvenile hormone mimic, is an effective larvicide against many pests of veterinary and public health importance. Pyriproxyfen is a biorational insecticide having many environmentally friendly attributes that make it compatible with integrated pest management programs. This experiment was performed for the assessment of resistance evolution and reversion toward susceptibility of Musca domestica to pyriproxyfen. Repeated selection at successive generations resulted in 5.09- and 130-fold increase in lethal concentration 50 (LC50) compared to field and susceptible strain, respectively. A significant decline after 22 generations without selection suggesting resistance to pyriproxyfen was unstable in M. domestica. Realized heritability (h (2)) of resistance to pyriproxyfen was 0.035 in pyriproxyfen-selected strain of M. domestica. The projected rate of resistance development indicated that, if slope = 1.28 and h (2) = 0.035, then 46-21 generations are required for 10-fold increase in LC50 at 50-90 % selection intensity. These findings suggest that a risk for resistance development to pyriproxyfen occurred in M. domestica under continuous selection pressure. Pyriproxyfen susceptibility reversed when its application is ceased for a specified duration.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Pakistan 1 5%
Unknown 19 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 15%
Other 2 10%
Student > Doctoral Student 2 10%
Professor 2 10%
Student > Ph. D. Student 2 10%
Other 4 20%
Unknown 5 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 45%
Biochemistry, Genetics and Molecular Biology 3 15%
Computer Science 1 5%
Unknown 7 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2014.
All research outputs
#18,382,900
of 22,769,322 outputs
Outputs from Parasitology Research
#2,370
of 3,780 outputs
Outputs of similar age
#187,768
of 262,191 outputs
Outputs of similar age from Parasitology Research
#42
of 88 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,780 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,191 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.