Title |
Effect of the olive oil phenol hydroxytyrosol on human hepatoma HepG2 cells
|
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Published in |
European Journal of Nutrition, January 2007
|
DOI | 10.1007/s00394-006-0633-8 |
Pubmed ID | |
Authors |
Luis Goya, Raquel Mateos, Laura Bravo |
Abstract |
Scientific evidence suggests that olive oil's beneficial effects are related to the high level of antioxidants, including phenolic compounds such as hydroxytyrosol. In vivo studies have shown that olive oil HTy is bioavailable and its biological activities, similar to those reported for other natural antioxidants such as quercetin, include prevention of LDL oxidation. Previous studies from our laboratory have shown that HTy and other phenolics in olive oil are absorbed and metabolized by cultured human hepatoma HepG2 cells where glucuronidated and methylated conjugates were the main derivatives formed, resembling the metabolic profile of olive oil phenols observed in human plasma and urine. |
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Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 14 | 18% |
Researcher | 12 | 15% |
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