@DrJMatthewRhett @covidtweets @mkobach @nycexpatmom Here is the info on guide seq https://t.co/Kv6lHpLBZf
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@manal_mehta @US_FDA @UrnovFyodor @sandymacrae23 Tagging DSBs is not novel, it has been used many times before, including with Guide-seq and Circle-Seq, developed by @JKeithJoung @JoungLab. https://t.co/cXaHCABNaW https://t.co/eZSXLLUVa5
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Collingwood- Computer predictions for off-target sites don't accurately predict all off-targets. Guide-Seq screen provides unbiased, genome wide off-target analysis. https://t.co/EhIq9RXVpR #CropBioEng18
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Collingwood- We've heard a lot in this symposium about off-target effects. Depending on your site, you could have 100s or 1000s of off-targets. Whether that matters depends on the application. https://t.co/EhIq9RXVpR #CropBioEng18