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Mendeley readers
Attention Score in Context
| Title |
Tryptophan synthase: a mine for enzymologists
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, April 2009
|
| DOI | 10.1007/s00018-009-0028-0 |
| Pubmed ID | |
| Authors |
Samanta Raboni, Stefano Bettati, Andrea Mozzarelli |
| Abstract |
Tryptophan synthase is a pyridoxal 5'-phosphate-dependent alpha(2)beta(2) complex catalyzing the last two steps of tryptophan biosynthesis in bacteria, plants and fungi. Structural, dynamic and functional studies, carried out over more than 40 years, have unveiled that: (1) alpha- and beta-active sites are separated by about 20 A and communicate via the selective stabilization of distinct conformational states, triggered by the chemical nature of individual catalytic intermediates and by allosteric ligands; (2) indole, formed at alpha-active site, is intramolecularly channeled to the beta-active site; and (3) naturally occurring as well as genetically generated mutants have allowed to pinpoint functional and regulatory roles for several individual amino acids. These key features have made tryptophan synthase a text-book case for the understanding of the interplay between chemistry and conformational energy landscapes. |
Mendeley readers
The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 2% |
| United Kingdom | 2 | 2% |
| Germany | 1 | <1% |
| Argentina | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 111 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 29 | 24% |
| Researcher | 21 | 18% |
| Student > Master | 14 | 12% |
| Student > Bachelor | 13 | 11% |
| Other | 8 | 7% |
| Other | 16 | 13% |
| Unknown | 18 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 30% |
| Biochemistry, Genetics and Molecular Biology | 19 | 16% |
| Chemistry | 18 | 15% |
| Neuroscience | 5 | 4% |
| Immunology and Microbiology | 4 | 3% |
| Other | 12 | 10% |
| Unknown | 25 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 January 2024.
All research outputs
#5,411,714
of 25,323,244 outputs
Outputs from Cellular and Molecular Life Sciences
#1,158
of 5,683 outputs
Outputs of similar age
#20,255
of 103,136 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#9
of 41 outputs
Altmetric has tracked 25,323,244 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,683 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,136 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.