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Biodegradation of bisphenol A and its halogenated analogues by Cunninghamella elegans ATCC36112

Overview of attention for article published in Biodegradation, May 2010
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Title
Biodegradation of bisphenol A and its halogenated analogues by Cunninghamella elegans ATCC36112
Published in
Biodegradation, May 2010
DOI 10.1007/s10532-010-9358-8
Pubmed ID
Authors

Young Soo Keum, Hye Ri Lee, Hee Won Park, Jeong-Han Kim

Abstract

Bisphenol A and its halogenated analogues are commonly used industrial chemicals with strong toxicological effects over many organisms. In this study, metabolic fate of bisphenol A and its halogenated analogues were evaluated with Cunninghamella elegans ATCC36112. Bisphenol A and related analogues were rapidly transformed into several metabolites by C. elegans within 2-4 days. Detailed analysis of metabolites reveals that both phase I and II metabolism occurred in C. elegans. Cytochrome P450-dependent hydroxylation was observed in BPA. However, major reaction with bisphenol A and analogues with 1-2 halogen atoms were the formation of glucose-conjugate, not being inhibited by cytochrome P450 inhibitor. Overall metabolic rates decreased with increasing number of substitution at 2- and 6-position of BPA structures, which may be consequences of limited bioavailability or steric hindrance to conjugate-forming reaction. Information from the current study will provide detailed insights over the fungal metabolism of BPA and analogues.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Unknown 29 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 27%
Student > Master 6 20%
Student > Ph. D. Student 3 10%
Student > Doctoral Student 2 7%
Professor 2 7%
Other 5 17%
Unknown 4 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 37%
Environmental Science 4 13%
Engineering 4 13%
Biochemistry, Genetics and Molecular Biology 3 10%
Materials Science 2 7%
Other 2 7%
Unknown 4 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2018.
All research outputs
#7,453,126
of 22,785,242 outputs
Outputs from Biodegradation
#61
of 368 outputs
Outputs of similar age
#34,321
of 95,281 outputs
Outputs of similar age from Biodegradation
#2
of 4 outputs
Altmetric has tracked 22,785,242 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 368 research outputs from this source. They receive a mean Attention Score of 2.6. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,281 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.