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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Glycogen Synthase Kinase-3 (GSK3): Inflammation, Diseases, and Therapeutics
|
|---|---|
| Published in |
Neurochemical Research, August 2006
|
| DOI | 10.1007/s11064-006-9128-5 |
| Pubmed ID | |
| Authors |
Richard S. Jope, Christopher J. Yuskaitis, Eléonore Beurel |
| Abstract |
Deciphering what governs inflammation and its effects on tissues is vital for understanding many pathologies. The recent discovery that glycogen synthase kinase-3 (GSK3) promotes inflammation reveals a new component of its well-documented actions in several prevalent diseases which involve inflammation, including mood disorders, Alzheimer's disease, diabetes, and cancer. Involvement in such disparate conditions stems from the widespread influences of GSK3 on many cellular functions, with this review focusing on its regulation of inflammatory processes. GSK3 promotes the production of inflammatory molecules and cell migration, which together make GSK3 a powerful regulator of inflammation, while GSK3 inhibition provides protection from inflammatory conditions in animal models. The involvement of GSK3 and inflammation in these diseases are highlighted. Thus, GSK3 may contribute not only to primary pathologies in these diseases, but also to the associated inflammation, suggesting that GSK3 inhibitors may have multiple effects influencing these conditions. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 400 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 1% |
| United Kingdom | 3 | <1% |
| China | 2 | <1% |
| Japan | 2 | <1% |
| Brazil | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| South Africa | 1 | <1% |
| France | 1 | <1% |
| Chile | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 383 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 72 | 18% |
| Researcher | 62 | 16% |
| Student > Bachelor | 59 | 15% |
| Student > Master | 56 | 14% |
| Professor > Associate Professor | 21 | 5% |
| Other | 53 | 13% |
| Unknown | 77 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 84 | 21% |
| Biochemistry, Genetics and Molecular Biology | 65 | 16% |
| Medicine and Dentistry | 50 | 13% |
| Neuroscience | 31 | 8% |
| Chemistry | 21 | 5% |
| Other | 60 | 15% |
| Unknown | 89 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 February 2021.
All research outputs
#1,865,521
of 24,315,442 outputs
Outputs from Neurochemical Research
#38
of 2,199 outputs
Outputs of similar age
#3,299
of 68,723 outputs
Outputs of similar age from Neurochemical Research
#2
of 11 outputs
Altmetric has tracked 24,315,442 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,199 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 68,723 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.