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Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function

Overview of attention for article published in Amino Acids, July 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

patent
2 patents
wikipedia
3 Wikipedia pages

Readers on

mendeley
70 Mendeley
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Title
Novel S100A7 (psoriasin)/S100A15 (koebnerisin) subfamily: highly homologous but distinct in regulation and function
Published in
Amino Acids, July 2010
DOI 10.1007/s00726-010-0666-4
Pubmed ID
Authors

Ronald Wolf, Thomas Ruzicka, Stuart H. Yuspa

Abstract

S100A7 (psoriasin) and S100A15 (koebnerisin) were first identified in inflamed psoriatic skin. They are of major interest because of their putative functional roles in innate immunity, epidermal cell maturation, and epithelial tumorigenesis. Human S100A7 and S100A15 have lately evolved by gene duplications within the epidermal differentiation complex (chromosome 1q21) during primate evolution forming a novel S100 subfamily. Therefore, S100A7 and S100A15 are almost identical in sequence (>90%) and are difficult to discriminate. Despite their high homology, S100A7 and S100A15 are distinct in tissue distribution, regulation, and function, and thus, exemplary for the diversity within the S100 family. Their different properties are compelling reasons to discriminate S100A7 (psoriasin) and S100A15 (koebnerisin) in epithelial homeostasis, inflammation, and cancer.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Belgium 1 1%
Unknown 68 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 21%
Student > Master 13 19%
Researcher 10 14%
Student > Doctoral Student 5 7%
Student > Bachelor 4 6%
Other 11 16%
Unknown 12 17%
Readers by discipline Count As %
Medicine and Dentistry 19 27%
Agricultural and Biological Sciences 19 27%
Biochemistry, Genetics and Molecular Biology 10 14%
Chemistry 4 6%
Computer Science 1 1%
Other 4 6%
Unknown 13 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2023.
All research outputs
#3,420,565
of 23,572,509 outputs
Outputs from Amino Acids
#190
of 1,534 outputs
Outputs of similar age
#12,968
of 95,440 outputs
Outputs of similar age from Amino Acids
#4
of 30 outputs
Altmetric has tracked 23,572,509 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,534 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 95,440 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.