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Purple acid phosphatases from bacteria: similarities to mammalian and plant enzymes

Overview of attention for article published in Gene, September 2000
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2 Wikipedia pages

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47 Mendeley
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Title
Purple acid phosphatases from bacteria: similarities to mammalian and plant enzymes
Published in
Gene, September 2000
DOI 10.1016/s0378-1119(00)00305-x
Pubmed ID
Authors

Gerhard Schenk, Michael L.J. Korsinczky, David A. Hume, Susan Hamilton, John DeJersey

Abstract

Mammalian and plant purple acid phosphatases have similar active site structures despite low sequence identity (<20%). Although no bacterial enzyme has been purified, a sequence database search revealed that genes that could encode potential purple acid phosphatases may be restricted to a small number of organisms (i.e. myco- and cyanobacteria). Analysis of their deduced amino acid sequences and predicted secondary structures indicates that the cyanobacterial enzyme is similar to both the mammalian and the recently discovered low-molecular-weight plant purple acid phosphatases, while the mycobacterial enzyme is homologous to the fungal and high-molecular-weight plant purple acid phosphatases. Homology models indicate that both bacterial proteins appear to be similar to mammalian purple acid phosphatases in the immediate vicinity of the active site. It is likely that these enzymes act as Fenton-type catalysts in order to prevent damage caused by reactive oxygen species generated by invaded host cells (M. tuberculosis) or by the light-harvesting complex (Synechocystis sp.).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Germany 1 2%
Brazil 1 2%
Unknown 44 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 26%
Researcher 9 19%
Student > Master 6 13%
Student > Bachelor 4 9%
Student > Doctoral Student 3 6%
Other 6 13%
Unknown 7 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 55%
Biochemistry, Genetics and Molecular Biology 9 19%
Chemistry 1 2%
Medicine and Dentistry 1 2%
Unknown 10 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2021.
All research outputs
#8,534,528
of 25,371,288 outputs
Outputs from Gene
#3,257
of 10,913 outputs
Outputs of similar age
#12,949
of 37,744 outputs
Outputs of similar age from Gene
#29
of 74 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,913 research outputs from this source. They receive a mean Attention Score of 3.8. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 37,744 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.