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A recent study hypothesized that sepsis consists of distinct subtypes. Gene expression pathway analysis of 700 patients found 3 unique clusters. https://t.co/njeHq0Umyn https://t.co/KHMw5FWFoa
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Second, we looked into published bulk RNAseq data in sepsis (h/t https://t.co/uT9WCsw82e ). You can’t find substates a priori from bulk RNAseq data – but having found them once by scRNAseq, we can look for unique signatures of each state (“bulk data deconv
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