Title |
Changes in the serum metabolite profile in obese children with weight loss
|
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Published in |
European Journal of Nutrition, April 2014
|
DOI | 10.1007/s00394-014-0698-8 |
Pubmed ID | |
Authors |
Thomas Reinehr, Barbara Wolters, Caroline Knop, Nina Lass, Christian Hellmuth, Ulrike Harder, Wolfgang Peissner, Simone Wahl, Harald Grallert, Jerzy Adamski, Thomas Illig, Cornelia Prehn, Zhonghao Yu, Rui Wang-Sattler, Berthold Koletzko |
Abstract |
Childhood obesity is an increasing problem and is accompanied by metabolic disturbances. Recently, we have identified 14 serum metabolites by a metabolomics approach (FIA-MS/MS), which showed altered concentrations in obese children as compared to normal-weight children. Obese children demonstrated higher concentrations of two acylcarnitines and lower levels of three amino acids, six acyl-alkyl phosphatidylcholines, and three lysophosphatidylcholines. The aim of this study was to analyze whether these alterations normalize in weight loss. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | 1% |
Ireland | 1 | <1% |
Unknown | 132 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 22 | 16% |
Student > Ph. D. Student | 21 | 16% |
Student > Master | 21 | 16% |
Student > Bachelor | 16 | 12% |
Student > Doctoral Student | 11 | 8% |
Other | 24 | 18% |
Unknown | 20 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 19% |
Agricultural and Biological Sciences | 22 | 16% |
Biochemistry, Genetics and Molecular Biology | 18 | 13% |
Nursing and Health Professions | 8 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
Other | 29 | 21% |
Unknown | 26 | 19% |