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Genetic Toxicology

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Cover of 'Genetic Toxicology'

Table of Contents

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    Book Overview
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    Chapter 1 The Application of Structure–Activity Relationships to the Prediction of the Mutagenic Activity of Chemicals
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    Chapter 2 Bacterial Mutagenicity Assays: Test Methods
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    Chapter 3 The Mouse Lymphoma Assay
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    Chapter 4 Mammalian Cell HPRT Gene Mutation Assay: Test Methods
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    Chapter 5 The In Vitro Mammalian Chromosome Aberration Test
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    Chapter 6 The Interpretation and Analysis of Cytogenetic Data
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    Chapter 7 The In Vitro Micronucleus Assay
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    Chapter 8 The In Vitro and In Vivo Comet Assays
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    Chapter 9 Assessment of DNA Interstrand Crosslinks Using the Modified Alkaline Comet Assay
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    Chapter 10 (32)P-postlabelling for the Sensitive Detection of DNA Adducts.
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    Chapter 11 Methods for the Detection of DNA Adducts
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    Chapter 12 The GADD45a-GFP GreenScreen HC Assay.
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    Chapter 13 Real-Time Reverse-Transcription Polymerase Chain Reaction: Technical Considerations for Gene Expression Analysis
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    Chapter 14 Cytogenetic In Vivo Assays in Somatic Cells
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    Chapter 15 Cytogenetic Methods in Human Biomonitoring: Principles and Uses
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    Chapter 16 The Measurement of Induced Genetic Change in Mammalian Germ Cells
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    Chapter 17 Transgenic Animal Mutation Models: A Review of the Models and How They Function
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    Chapter 18 Analysis of Genotoxicity Data in a Regulatory Context
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