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High Throughput Screening

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Cover of 'High Throughput Screening'

Table of Contents

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    Book Overview
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    Chapter 1 Design and Implementation of High-Throughput Screening Assays
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    Chapter 2 Characterization of Inhibitor Binding Through Multiple Inhibitor Analysis: A Novel Local Fitting Method
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    Chapter 3 High Throughput Screening
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    Chapter 4 Structure-Based Virtual Screening of Commercially Available Compound Libraries
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    Chapter 5 AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions
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    Chapter 6 Instrument Quality Control
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    Chapter 7 Application of Fluorescence Polarization in HTS Assays
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    Chapter 8 Time-Resolved Fluorescence Assays
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    Chapter 9 Protein Kinase Selectivity Profiling Using Microfluid Mobility Shift Assays
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    Chapter 10 Screening for Inhibitors of Kinase Autophosphorylation
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    Chapter 11 A Fluorescence-Based High-Throughput Screening Assay to Identify Growth Inhibitors of the Pathogenic Fungus Aspergillus fumigatus
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    Chapter 12 High Throughput Screening
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    Chapter 13 Identification of State-Dependent Blockers for Voltage-Gated Calcium Channels Using a FLIPR-Based Assay
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    Chapter 14 A Luciferase Reporter Gene System for High-Throughput Screening of γ -Globin Gene Activators
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    Chapter 15 A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3′,5′-Cyclic Adenosine Monophosphate Efflux
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    Chapter 16 High-Throughput Cell Toxicity Assays
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    Chapter 17 BRET: NanoLuc-Based Bioluminescence Resonance Energy Transfer Platform to Monitor Protein-Protein Interactions in Live Cells
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    Chapter 18 Application of Imaging-Based Assays in Microplate Formats for High-Content Screening
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