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Mendeley readers
Attention Score in Context
| Title |
Embryo culture media and IVF/ICSI success rates: a systematic review
|
|---|---|
| Published in |
Human Reproduction Update, February 2013
|
| DOI | 10.1093/humupd/dms061 |
| Pubmed ID | |
| Authors |
E. Mantikou, M.A.F.M. Youssef, M. van Wely, F. van der Veen, H.G. Al-Inany, S. Repping, S. Mastenbroek |
| Abstract |
BACKGROUND The media that are used to culture human preimplantation embryos are considered to be an important factor for the success rates of IVF/ICSI. Here, we present a systematic review of randomized controlled trials (RCTs) on the effect of culture media on IVF/ICSI success rates. METHODS RCTs published between January 1985 and July 2012 were eligible for inclusion. The primary outcome was live birth. Secondary outcomes were health of babies born, ongoing pregnancies, clinical pregnancies, miscarriages, multiple pregnancies, implantation rate, cryopreservation rate, embryo quality and fertilization rate. For those media that were evaluated in more than one comparison, an unconventional meta-analysis was performed by pooling the data of the media they were compared to. RESULTS Twenty-two RCTs were included that evaluated 31 different comparisons. Conventional meta-analysis was not possible for any of the outcomes as nearly all trials compared different culture media. Only four trials reported on live birth, and one of them reported a significant difference. Nine trials reported on ongoing and/or clinical pregnancy rates, of which four showed a significant difference. Pooling the data did not reveal a superior culture medium. CONCLUSIONS It is yet unknown what culture medium leads to the best success rates in IVF/ICSI. Given the potential importance of culture media for treatment outcome, rigorously designed RCTs are needed for currently available, as well as newly introduced culture media. |
Mendeley readers
The data shown below were compiled from readership statistics for 177 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Poland | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 173 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 28 | 16% |
| Student > Ph. D. Student | 23 | 13% |
| Researcher | 23 | 13% |
| Student > Master | 23 | 13% |
| Other | 9 | 5% |
| Other | 32 | 18% |
| Unknown | 39 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 47 | 27% |
| Agricultural and Biological Sciences | 34 | 19% |
| Biochemistry, Genetics and Molecular Biology | 32 | 18% |
| Nursing and Health Professions | 4 | 2% |
| Social Sciences | 4 | 2% |
| Other | 16 | 9% |
| Unknown | 40 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2013.
All research outputs
#8,535,684
of 25,374,917 outputs
Outputs from Human Reproduction Update
#685
of 1,072 outputs
Outputs of similar age
#89,182
of 291,277 outputs
Outputs of similar age from Human Reproduction Update
#14
of 17 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,072 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,277 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.