↓ Skip to main content

Effektives Management eines Ausbruchs mit multiresistenten Klebsiella pneumoniae in der Neurorehabilitation

Overview of attention for article published in Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, April 2018
Altmetric Badge

Mentioned by

twitter
1 X user

Readers on

mendeley
26 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Effektives Management eines Ausbruchs mit multiresistenten Klebsiella pneumoniae in der Neurorehabilitation
Published in
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, April 2018
DOI 10.1007/s00103-018-2728-9
Pubmed ID
Authors

Christian Dohle, Gerit Korr, Michael Friedrichs, Volker Kullmann, Mei-Lin Tung, Martin Kaase, Holger Rüssmann, Dagmar Sissolak, Dirk Werber, Laura Becker, Stephan Fuchs, Yvonne Pfeifer, Torsten Semmler, Gudrun Widders, Tim Eckmanns, Guido Werner, Edith Zill, Sebastian Haller

Abstract

In addition to acute care hospitals, rehabilitation centres are increasingly confronted with multi-resistant pathogens. Long durations of stay and intensive treatments impose special hygienic challenges. We investigated an extended spectrum beta-lactamase-Klebsiella pneumoniae (ESBL-K. pneumoniae) outbreak in a neurorehabilitation centre. We defined confirmed cases as patients who stayed in the centre during the outbreak period and from whom ESBL-K. pneumoniae was isolated with the outbreak sequence type. Probable cases had an epidemiological link to at least one confirmed case but no isolate for typing. Next generation sequencing (NGS) was performed on 53 isolates from patients. Environmental sampling was performed. Systematic microbiological screening was implemented and ESBL-K. pneumoniae-positive patients were cohorted in a designated ward. We identified 30 confirmed and 6 probable cases. NGS revealed three genetic clusters: Cluster 1 - the outbreak cluster - with isolates of 30 cases (sequence type ST15), Cluster 2 with 7 patients (ST405) and Cluster 3 with 8 patients (ST414). In two patients, the outbreak strain developed further antibiotic resistance, one with colistin resistance and the other carbapenem resistance. The outbreak ceased after strict isolation measures. Epidemiology and NGS results paired with the effectiveness of cohorting suggest that transmission occurred mainly from person to person in this outbreak. There was an apparent association of the probability to acquire ESBL-K. pneumoniae and treatment intensity, whereas infection rate was related to morbidity. The identification of the outbreak clone and additional clusters plus the development of additional antibiotic resistance shows the relevance of NGS and highlights the need for timely and efficient outbreak management.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 26 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 26 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 31%
Student > Bachelor 4 15%
Other 2 8%
Student > Ph. D. Student 2 8%
Student > Doctoral Student 1 4%
Other 3 12%
Unknown 6 23%
Readers by discipline Count As %
Medicine and Dentistry 8 31%
Immunology and Microbiology 4 15%
Nursing and Health Professions 1 4%
Economics, Econometrics and Finance 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Other 4 15%
Unknown 7 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2018.
All research outputs
#18,601,965
of 23,041,514 outputs
Outputs from Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz
#740
of 937 outputs
Outputs of similar age
#255,568
of 329,292 outputs
Outputs of similar age from Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz
#13
of 15 outputs
Altmetric has tracked 23,041,514 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 937 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,292 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.