Title |
WITHDRAWN: Anticonvulsants for cocaine dependence
|
---|---|
Published in |
Cochrane database of systematic reviews, March 2015
|
DOI | 10.1002/14651858.cd006754.pub3 |
Pubmed ID | |
Authors |
Silvia Minozzi, Laura Amato, Marina Davoli, Michael F Farrell, Anelise Arl Lima Reisser, Pier Paolo Pani, Mauricio Silva de Lima, Bernardo Go Soares, Simona Vecchi |
Abstract |
Cocaine dependence is a major public health problem that is characterized by recidivism and a host of medical and psychosocial complications. Although effective pharmacotherapy is available for alcohol and heroin dependence none exists currently for cocaine dependence despite two decades of clinical trials primarily involving antidepressant, anti convulsivant and dopaminergic medications. There has been extensive consideration of optimal pharmacological approaches to the treatment of cocaine dependence with consideration of both dopamine antagonists and agonists. Anticonvulsants have been candidates for the treatment of addiction based on the hypothesis that seizure kindling-like mechanisms contribute to addiction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 4% |
Argentina | 1 | 4% |
Unknown | 22 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 21% |
Student > Doctoral Student | 4 | 17% |
Other | 3 | 13% |
Professor | 3 | 13% |
Student > Ph. D. Student | 3 | 13% |
Other | 4 | 17% |
Unknown | 2 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 46% |
Neuroscience | 5 | 21% |
Nursing and Health Professions | 1 | 4% |
Computer Science | 1 | 4% |
Psychology | 1 | 4% |
Other | 3 | 13% |
Unknown | 2 | 8% |