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Potential role of miR-100 in cancer diagnosis, prognosis, and therapy

Overview of attention for article published in Tumor Biology, March 2015
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Title
Potential role of miR-100 in cancer diagnosis, prognosis, and therapy
Published in
Tumor Biology, March 2015
DOI 10.1007/s13277-015-3267-8
Pubmed ID
Authors

Chu Qin, Ru-Yi Huang, Zhao-Xia Wang

Abstract

MicroRNAs (miRNAs) are small non-coding RNAs that function by base pairing with messenger RNAs, thereby regulating protein expression. Functional studies indicate that miRNAs are involved in the regulation of almost every biological pathway. Moreover, changes in miRNA expression are associated with several human pathologies, including cancer. Dysregulation and aberrant expression of microRNA-100 (miR-100) have been reported to be involved in tumorigenesis and tumor progression of several cancer types, suggesting that miR-100 might serve as a diagnostic and/or prognostic marker for human malignancy. In this review, we summarize the potential application of miR-100 in cancer treatment and as a new molecular marker for cancer prognosis and diagnosis. We will provide a brief introduction to miR-100 and discuss its role as a non-invasive biomarker and a potential therapeutic target in human cancers.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 34%
Student > Master 6 17%
Researcher 4 11%
Student > Postgraduate 2 6%
Student > Bachelor 1 3%
Other 5 14%
Unknown 5 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 23%
Medicine and Dentistry 8 23%
Biochemistry, Genetics and Molecular Biology 7 20%
Materials Science 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 2 6%
Unknown 6 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2015.
All research outputs
#20,263,155
of 22,793,427 outputs
Outputs from Tumor Biology
#1,834
of 2,622 outputs
Outputs of similar age
#217,516
of 257,881 outputs
Outputs of similar age from Tumor Biology
#97
of 170 outputs
Altmetric has tracked 22,793,427 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,622 research outputs from this source. They receive a mean Attention Score of 2.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 257,881 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 170 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.